On the representation dimension of monomial and self-injective special multiserial algebras See

For a monomial special multiserial algebra, which in general is of wild representation type, we construct a radical embedding into an algebra of finite representation type. As a consequence, we show that the representation dimension of monomial and self-injective special multiserial algebras is less than or equal to three.

Schroll, Sibylle

Almost gentle algebras and their trivial extensions See

In this paper we define almost gentle algebras. They are monomial special multiserial algebras generalizing gentle algebras. We show that the trivial extension of an almost gentle algebra by its minimal injective co-generator is a symmetric special multiserial algebra and hence a Brauer configuration algebra. Conversely, we show that admissible cuts of Brauer configuration algebras give rise to gentle algebras and as a consequence, we obtain that every Brauer configuration algebra with multip...

Green, Edward L.; Schroll, Sibylle

Brauer configuration algebras: A generalization of Brauer graph algebras See

In this paper we introduce a generalization of a Brauer graph algebra which we call a Brauer configuration algebra. As with Brauer graphs and Brauer graph algebras, to each Brauer configuration, there is an associated Brauer configuration algebra. We show that Brauer configuration algebras are finite dimensional symmetric algebras. After studying and analysing structural properties of Brauer configurations and Brauer configuration algebras, we show that a Brauer configuration algebra is multi...

Green, Edward L.; Schroll, Sibylle

Special multiserial algebras, Brauer configuration algebras and more : a survey See

We survey results on multiserial algebras, special multiserial algebras and Brauer configuration algebras. A structural property of modules over a special multiserial algebra is presented. Almost gentle algebras are introduced and we describe some results related to this class of algebras. We also report on the structure of radical cubed zero symmetric algebras.

Green, Edward L.; Schroll, Sibylle

Brauer graph algebras See

These lecture notes on Brauer graph algebras are the result of a series of four lectures given at the CIMPA research school in Mar del Plata, Argentina, in March 2016. After motivating the study of Brauer graph algebras by relating them to special biserial algebras, the definition of Brauer graph algebras is given in great detail with many examples to illustrate the concepts. This is followed by a short section on the interpretation of Brauer graphs as decorated ribbon graphs. A section on ge...

Schroll, Sibylle

A Novel Role of Matrix Metalloproteinase-8 in Macrophage Differentiation and Polarization. See

Matrix metalloproteinase-8 (MMP8) has been shown to influence various cellular functions. As monocytes and macrophages (Mφ) express MMP8, we investigated if MMP8 played a role in macrophage differentiation and polarization. MMP8 expression was significantly increased during monocyte differentiation into Mφ. Monocyte-derived Mφ from MMP8-deficient mice expressed higher levels of M1-Mφ markers but lower levels of M2-Mφ markers than monocyte-derived Mφ from wild-type mice. Although Mφ from eithe...

Wen, Guanmei; Zhang, Cheng; Chen, Qishan; Luong, Le Anh; Mustafa, Arif... et al.

Analysis of Reaction Intermediates in Tryptophan 2,3-Dioxygenase: A Comparison with Indoleamine 2,3-Dioxygenase. See

Indoleamine 2,3-dioxygenase (IDO) and tryptophan 2,3-dioxygenase (TDO) are heme-containing enzymes that catalyze the O2-dependent oxidation of l-tryptophan (l-Trp) in biological systems. Although many decades have passed since their discovery, the mechanism of tryptophan oxidation has not been established. It has been widely assumed that IDO and TDO react using the same mechanism, although there is no evidence that they do. For IDO, a Compound II (ferryl) species accumulates in the steady sta...

Basran, Jaswir; Booth, Elizabeth S.; Lee, Michael; Handa, Sandeep; Raven, Emma L.

Survival in South Asian and white European patients after acute myocardial infarction; a UK historical cohort study. See

Objective To examine the association between ethnicity and survival following acute myocardial infarction (AMI) in White European (WE) and South Asian (SA) patients from a multiethnic UK population. Methods Retrospective, cohort study of 4111 (N=730, 17.8% of SA ethnicity) hospitalised patients, with AMI from a tertiary coronary care centre in the UK, admitted between October 2002 and September 2008. The primary end point was all-cause mortality. The association of ethnicity with survival ...

Gholap, Nitin N.; Khunti, Kamlesh; Davies, Melanie J.; Bodicoat, Danielle H .; Squire, Iain B.

Coronal and heliospheric magnetic flux circulation and its relation to open solar flux evolution See

Solar cycle 24 is notable for three features that can be found in previous cycles but which have been unusually prominent: (1) sunspot activity was considerably greater in the northern/southern hemisphere during the rising/declining phase; (2) accumulation of open solar flux (OSF) during the rising phase was modest, but rapid in the early declining phase; (3) the heliospheric current sheet (HCS) tilt showed large fluctuations. We show that these features had a major influence on the progressi...

Lockwood, Mike; Owens, Mathew J.; Imber, Suzanne M.; James, Matthew K.; Bunce, Emma J.... et al.

The social practice of rescue: the safety implications of acute illness trajectories and patient categorisation in medical and maternity settings See

The normative position in acute hospital care when a patient is seriously ill is to resuscitate and rescue. However, a number of UK and international reports have highlighted problems with the lack of timely recognition, treatment and referral of patients whose condition is deteriorating while being cared for on hospital wards. This article explores the social practice of rescue, and the structural and cultural influences that guide the categorisation and ordering of acutely ill patients in d...

Mackintosh, Nicola; Sandall, Jane

Adaptivity and blow-up detection for nonlinear evolution problems See

This work is concerned with the development of a space-time adaptive numerical method, based on a rigorous a posteriori error bound, for a semilinear convection-diffusion problem which may exhibit blow-up in finite time. More specifically, a posteriori error bounds are derived in the $L^{\infty}(L^2)+L^2(H^1)$-type norm for a first order in time implicit-explicit interior penalty discontinuous Galerkin in space discretization of the problem, although the theory presented is directly applicabl...

Cangiani, Andrea; Georgoulis, Emmanuil H.; Kyza, Irene; Metcalfe, Stephen

Engagement in the Knowledge Economy: Regional Patterns of Content Creation with a Focus on Sub-Saharan Africa See

Increasing digital connectivity has sparked many hopes for the democratization of information and knowledge production in sub-Saharan Africa. To investigate the patterns of knowledge creation in the region compared to other world regions, we examine three key metrics: spatial distributions of academic articles (traditional knowledge production), collaborative software development, and Internet domain registrations (digitally mediated knowledge production). We find that, contrary to the expect...

De Sabbata, S; Ojanperä, S; Graham, M; Straumann, R

Aging and the Optimal Viewing Position Effect in Visual Word Recognition: Evidence from English See

Words are recognized most efficiently by young adults when fixated at an optimal viewing position (OVP), which for English is between a word’s beginning and middle letters. How this OVP effect changes with age is unknown but may differ for older adults due to visual declines in later life. Accordingly, a lexical decision experiment was conducted in which short (5-letter) and long (9-letter) words were fixated at various letter positions. The older adults produced slower responses. But, crucia...

Li, Lin; Li, Sha; Wang, Jingxin; McGowan, Victoria A.; Liu, Pingping... et al.

Metabolic Remodeling in Diabetic Cardiomyopathy See

Diabetes is a risk factor for heart failure and cardiovascular mortality with specific changes to myocardial metabolism, energetics, structure, and function. The gradual impairment of insulin production and signalling in diabetes is associated with elevated plasma fatty acids and increased myocardial free fatty acid uptake and activation of the transcription factor PPARα. The increased free fatty acid uptake results in accumulation of toxic metabolites, such as ceramide and diacylglycerol, ac...

Chong, Cher-Rin; Clarke, Kieran; Levelt, Eylem

Accumbal Cholinergic Interneurons Differentially Influence Motivation Related to Satiety Signaling See

Satiety, rather than all or none, can instead be viewed as a cumulative decrease in the drive to eat that develops over the course of a meal. The nucleus accumbens (NAc) is known to play a critical role in this type of value reappraisal, but the underlying circuits that influence such processes are unclear. Although NAc cholinergic interneurons (CINs) comprise only a small proportion of NAc neurons, their local impact on reward-based processes provides a candidate cell population for investig...

Aitta-Aho, Teemu; Phillips, Benjamin U.; Pappa, Elpiniki; Hay, Y. Audrey; Harnischfeger, Fiona... et al.

Vitamin D3 supplementation of a high fat high sugar diet ameliorates prediabetic phenotype in female LDLR(-/-) and LDLR(+/+) mice See

INTRODUCTION: Fatty liver disease is prevalent in populations with high caloric intake. Nutritherapeutic approaches are being considered, such as supplementary Vitamin D3 , to improve aspects of metabolic syndrome, namely fatty liver disease, hyperlipidemia, and insulin resistance associated with obesity. METHODS: We analyzed female LDLR(-/-) and LDLR(+/+) mice on a 10-week diabetogenic diet for markers of fatty liver disease, metabolic strain, and inflammation. RESULTS: The groups on a high ...

Kheder, Ramiar; Hobkirk, James; Saeed, Zeayd; Janus, Justyna; Carroll, Sean... et al.

Corrigendum: Transcriptome Analysis of Hamelia patens (Rubiaceae) Anthers Reveals Candidate Genes for Tapetum and Pollen Wall Development See

This corrects the article archived at http://hdl.handle.net/2381/39808.

Yue, Lin; Twell, David; Kuang, Yanfeng; Liao, Jingping; Zhou, Xianqiang

“Vulnerable by law (but not by nature)”: examining perceptions of youth and childhood ‘vulnerability’ in the context of police custody See

This paper, drawing upon qualitative data produced through interviews with custody officers (COs) at two custody suites in England, examines how the vulnerability of children and young people is conceptualised generally, within the criminal process, and then, more specifically, in police custody. It uses the appropriate adult (AA) safeguard under Code C to the Police and Criminal Evidence Act 1984 as the point of reference and explores, firstly, how childhood is conceptualised and, secondly, ...

Dehaghani, Roxanna

Hijacking the Narrative: The First World Forum on Natural Capital, #natcap13, and Radical Dissent See

The first World Forum on Natural Capital (WFNC) was an important moment in the production of “valued” nature. It brought together bankers, CEOs, and business elites to promote financialized environmental accounting as a solution to ecosystem degradation. Anti-capitalist activists, however, opposed the further intrusion of economic logic to environmental decision-making and resisted its progression. While WFNC organizers were able to advance the concept of “natural capital” through traditional...

Matulis, Brett S.; Moyer, Jessica R.