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Title: Determinants of induced sputum neutrophil differential count in healthy children: role of interleukin-8 and oxidative stress
Authors: Kulkarni, Neeta
Cooke, Marcus S.
Grigg, Jonathan
First Published: Oct-2007
Publisher: Elsevier
Citation: Respiratory Medicine, 2007, 101(10), pp.2108-2112
Abstract: In healthy children, there is a wide range in the induced sputum neutrophil differential count. To date, the reason for this is unclear. In animal models, neutrophil chemoattractant cytokines and oxidative stress are major determinants of airway neutrophilia. In this study, we therefore aimed to assess the association between interleukin-8, and the oxidative stress marker 8-oxo-7, 8-dihydro-2’-deoxyguanosine (8-oxodG), with the neutrophil count in induced sputum samples from healthy children.
DOI Link: 10.1016/j.rmed.2007.05.018
Type: Article
Rights: This is the authors' final draft of the paper published as Respiratory Medicine, 2007, 101(10), pp. 2108-2112, which was titled "Neutrophils in induced sputum from healthy children: Role of interleukin-8 and oxidative stress". The final definitive version is available from, DOI: 10.1016/j.rmed.2007.05.018
Appears in Collections:Published Articles, Dept. of Cancer Studies and Molecular Medicine
Published Articles, Dept. of Infection, Immunity and Inflammation

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