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First PublishedTitleAuthor(s)Type
Jan-2012Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targetsJiang, M; Wang, J; Fu, J; Xiang, L; Peng, Q; Arbez, N; Zhu, S; Sommers, K; Qian, J; Ross, CA; Duan, W; Wang, J; Du, L; Cichewicz, RH; Jeong, H; Krainc, D; West, T; Holtzman, DM; Hou, Z; Zhang, J; Mori, S; Cai, H; Martin, B; Seredenina, T; Luthi-Carter, R; Yang, XW; Tamashiro, KLK; Moran, TH; Aja, S; Maudsley, S; Mattson, MP; Ross, CA; Ross, CA; Ross, CA; Ross, CA; Duan, WJournal Article
17-Jun-2011A brain-permeable small molecule reduces neuronal cholesterol by inhibiting activity of sirtuin 2 deacetylase.Taylor, DM; Balabadra, U; Xiang, Z; Woodman, B; Meade, S; Amore, A; Maxwell, MM; Reeves, S; Bates, GP; Luthi-Carter, R; Lowden, PA; Kazantsev, AGJournal Article
27-Apr-2010SIRT2 inhibition achieves neuroprotection by decreasing sterol biosynthesis.Luthi-Carter, R; Taylor, DM; Pallos, J; Lambert, E; Amore, A; Parker, A; Moffitt, H; Smith, DL; Runne, H; Gokce, O; Kuhn, A; Xiang, Z; Maxwell, MM; Reeves, SA; Bates, GP; Neri, C; Thompson, LM; Marsh, JL; Kazantsev, AGJournal Article
Oct-2009Diminished hippocalcin expression in Huntington's disease brain does not account for increased striatal neuron vulnerability as assessed in primary neurons.Rudinskiy, N; Kaneko, YA; Beesen, AA; Gokce, O; Régulier, E; Déglon, N; Luthi-Carter, RJournal Article
Aug-2010Developmental expression of Synaptotagmin isoforms in single calyx of Held-generating neurons.Xiao, L; Han, Y; Runne, H; Murray, H; Kochubey, O; Luthi-Carter, R; Schneggenburger, RJournal Article
Jul-2010Novel gamma-secretase inhibitors uncover a common nucleotide-binding site in JAK3, SIRT2, and PS1.Wu, F; Schweizer, C; Rudinskiy, N; Taylor, DM; Kazantsev, A; Luthi-Carter, R; Fraering, PCJournal Article
15-Apr-2010Transcriptional changes in Huntington disease identified using genome-wide expression profiling and cross-platform analysis.Becanovic, K; Pouladi, MA; Lim, RS; Kuhn, A; Pavlidis, P; Luthi-Carter, R; Hayden, MR; Leavitt, BRJournal Article
Apr-2010Cell loss in the motor and cingulate cortex correlates with symptomatology in Huntington's disease.Thu, DC; Oorschot, DE; Tippett, LJ; Nana, AL; Hogg, VM; Synek, BJ; Luthi-Carter, R; Waldvogel, HJ; Faull, RLJournal Article
Dec-2003Complex alteration of NMDA receptors in transgenic Huntington's disease mouse brain: Analysis of mRNA and protein expression, plasma membrane association, interacting proteins, and phosphorylationLuthi-Carter, R; Dunah, AW; DeJohn, MM; Farrell, LA; Young, AB; Standaert, DG; Cha, J-HJ; Apostol, BL; Thompson, LM; Bates, GPJournal Article
15-Jun-2002Differential D and D receptor-mediated effects on immediate early gene induction in a transgenic mouse model of Huntington's diseaseSpektor, BS; Miller, DW; Hollingsworth, ZR; Kaneko, YA; Solano, SM; Johnson, JM; Enney, JB; Young, AB; Luthi-Carter, RJournal Article