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Results 1-10 of 16 (Search time: 0.001 seconds).
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First PublishedTitleAuthor(s)Type
21-Nov-2006Combined hERG channel inhibition and disruption of trafficking in drug-induced long QT syndrome by fluoxetine: A case-study in cardiac safety pharmacologyHancox, JC; Mitcheson, JSJournal Article
Jul-2003Drug binding to HERG channels: Evidence for a 'non-aromatic' binding site for fluvoxamineMitcheson, JSJournal Article
2001Molecular biology of K channels and their role in cardiac arrhythmiasTristani-Firouzi, M; Chen, J; Mitcheson, JS; Sanguinetti, MC; Sanguinetti, MCJournal Article
15-Jul-2008Insight into the mechanism of inactivation and pH sensitivity in potassium channels from molecular dynamics simulationsStansfeld, PJ; Mitcheson, JS; Stansfeld, PJ; Grottesi, A; Sands, ZA; Sansom, MSP; Gedeck, P; Gosling, M; Cox, B; Stanfield, PR; Sutcliffe, MJ; Grottesi, A; Sands, ZAJournal Article
1-Aug-2007Drug block of the hERG potassium channel: Insight from modelingStansfeld, PJ; Mitcheson, JS; Gedeck, P; Gosling, M; Cox, B; Sutcliffe, MJ; Sutcliffe, MJ; Sutcliffe, MJJournal Article
Mar-2005Predicting drug-hERG channel interactions that cause acquired long QT syndromeSanguinetti, MC; Mitcheson, JSJournal Article
2-Nov-2007Activation gating of hERG potassium channels: S6 glycines are not required as gating hingesHardman, RM; Dalibalta, S; Mitcheson, JS; Stansfeld, PJ; Sutcliffe, MJJournal Article
2006Molecular mechanisms for drug interactions with hERG that cause long QT syndromeStansfeld, PJ; Mitcheson, JS; Sutcliffe, MJJournal Article
May-2006Molecular determinants of hERG channel blockKamiya, K; Niwa, R; Mitcheson, JS; Sanguinetti, MCJournal Article
25-Sep-2001The S4-S5 linker couples voltage sensing and activation of pacemaker channelsChen, J; Mitcheson, JS; Tristani-Firouzi, M; Lin, M; Sanguinetti, MCJournal Article