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First PublishedTitleAuthor(s)Type
18-Jul-2008Cysteine substitution mutagenesis and the effects of methanethiosulfonate reagents at P2X2 and P2X4 receptors support a core common mode of ATP action at P2X receptors.Roberts, JA; Digby, HR; Kara, M; El Ajouz S; Sutcliffe, MJ; Evans, RJJournal Article
Mar-2005Mutagenesis studies of conserved proline residues of human P2X receptors for ATP indicate that proline 272 contributes to channel function.Roberts, JA; Evans, RJJournal Article
May-2009Contribution of the region Glu181 to Val200 of the extracellular loop of the human P2X1 receptor to agonist binding and gating revealed using cysteine scanning mutagenesis.Roberts, JA; Valente, M; Allsopp, RC; Watt, D; Evans, RJJournal Article
Jan-2009Regions of the amino terminus of the P2X receptor required for modification by phorbol ester and mGluR1alpha receptors.Wen, H; Evans, RJJournal Article
1-Mar-2002P2X(1) receptor subunit contribution to gating revealed by a dominant negative PKC mutant.Ennion, SJ; Evans, RJJournal Article
19-Aug-2011Cysteine scanning mutagenesis (residues Glu52-Gly96) of the human P2X1 receptor for ATP: mapping agonist binding and channel gating.Allsopp, RC; El Ajouz S; Schmid, R; Evans, RJJournal Article
Jan-2012Molecular basis of selective antagonism of the P2X1 receptor for ATP by NF449 and suramin: contribution of basic amino acids in the cysteine-rich loop.El-Ajouz, S; Ray, D; Allsopp, RC; Evans, RJJournal Article
16-Jan-2015Use of chimeras, point mutants, and molecular modeling to map the antagonist-binding site of 4,4',4″,4‴-(carbonylbis-(imino-5,1,3-benzenetriylbis(carbonylimino)))tetrakisbenzene-1,3-disulfonic acid (NF449) at P2X1 receptors for ATP.Farmer, Louise K.; Schmid, Ralf; Evans, Richard J.Journal Article
21-Dec-2010Contribution of the intracellular C terminal domain to regulation of human P2X1 receptors for ATP by phorbol ester and Gq coupled mGlu(1α) receptors.Wen, H; Evans, RJJournal Article