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Title: Pharmacological characterization of the bifunctional opioid ligand H-Dmt-Tic-Gly-NH-Bzl (UFP-505).
Authors: Dietis, N
McDonald, J
Molinari, S
Calo, G
Guerrini, R
Rowbotham, DJ
Lambert, DG
First Published: Feb-2012
Citation: BR J ANAESTH, 2012, 108 (2), pp. 262-270
Abstract: While producing good-quality analgesia, µ-opioid (MOP) receptor activation produces a number of side-effects including tolerance. Simultaneous blockade of δ-opioid (DOP) receptors has been shown to reduce tolerance to morphine. Here, we characterize a prototype bifunctional opioid H-Dmt-Tic-Gly-NH-Bzl (UFP-505).
DOI Link: 10.1093/bja/aer377
eISSN: 1471-6771
Type: Journal Article
Appears in Collections:Published Articles, Dept. of Health Sciences

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