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|Title:||Multiple domain insertions and losses in the evolution of the Rab prenylation complex.|
|Citation:||BMC EVOL BIOL, 2007, 7, pp. 140-140|
|Abstract:||Rab proteins are regulators of vesicular trafficking, requiring a lipid modification for proper function, prenylation of C-terminal cysteines. This is catalysed by a complex of a catalytic heterodimer (Rab Geranylgeranyl Transferase - RabGGTase) and an accessory protein (Rab Escort Protein. REP). Components of this complex display domain insertions relative to paralogous proteins. The function of these inserted domains is unclear.|
|Appears in Collections:||Published Articles, School of Historical Studies|
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