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Title: An esterase-activated magnetic resonance contrast agent.
Authors: Giardiello, M
Lowe, MP
Botta, M
First Published: 21-Oct-2007
Citation: CHEM COMMUN (CAMB), 2007 (39), pp. 4044-4046
Abstract: A Gd(III) complex bearing pendant acetoxymethyl esters is activated on exposure to porcine liver esterase; the 84% increase in relaxivity is a result of suppression of HCO(3)(-)/CO(3)(2-) binding by the resulting negative charge.
DOI Link: 10.1039/b711989e
ISSN: 1359-7345
Type: Journal Article
Appears in Collections:Published Articles, Dept. of Chemistry

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