Please use this identifier to cite or link to this item: http://hdl.handle.net/2381/13569
Title: Endotoxaemia in haemodialysis: a novel factor in erythropoetin resistance?
Authors: Harrison, L. E.
Burton, J. O.
Szeto, C. C.
Li, P. K.
McIntyre, C. W.
First Published: 29-Jun-2012
Publisher: Public Library of Science
Citation: PLOS ONE, 2012, 7 (6), p. e40209
Abstract: Translocated endotoxin derived from intestinal bacteria is a driver of systemic inflammation and oxidative stress. Severe endotoxaemia is an underappreciated, but characteristic finding in haemodialysis (HD) patients, and appears to be driven by acute repetitive dialysis induced circulatory stress. Resistance to erythropoietin (EPO) has been identified as a predictor of mortality risk, and associated with inflammation and malnutrition. This study aims to explore the potential link between previously unrecognised endotoxaemia and EPO Resistance Index (ERI) in HD patients.
DOI Link: 10.1371/journal.pone.0040209
eISSN: 1932-6203
Links: http://hdl.handle.net/2381/13569
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0040209
Version: Publisher Version
Status: Peer-reviewed
Type: Journal Article
Rights: Copyright © 2012 Harrison et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Appears in Collections:Published Articles, Dept. of Infection, Immunity and Inflammation

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