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Title: Break force and tensile strength relationships for curved faced tablets subject to diametrical compression.
Authors: Shang, C
Sinka, IC
Jayaraman, B
Pan, J
First Published: 11-Sep-2012
Citation: INT J PHARM, 2012
Abstract: The break force of flat faced tablets subject to diametrical compression (often referred to as "hardness") can be related to the tensile strength of the material using the Hertz contact theory. For curved tablets analytical solutions do not exist and an empirical equation developed by Pitt is usually used. In this paper we measure the break force of curved faced tablets having a range of curvatures pressed at various compaction forces. An empirical equation is proposed to relate the break force of curved faced tablets to the material tensile strength. The proposed equation is simplified and reduced to a form that is consistent with Hertz theory for flat faced tablets.
DOI Link: 10.1016/j.ijpharm.2012.09.005
eISSN: 1873-3476
Type: Journal Article
Appears in Collections:Published Articles, Dept. of Engineering

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