Please use this identifier to cite or link to this item: http://hdl.handle.net/2381/14291
Title: Differential expression of immune defences is associated with specific host-parasite interactions in insects.
Authors: Riddell, Carolyn
Adams, S.
Schmid-Hempel, P.
Mallon, Eamonn B.
First Published: 27-Oct-2009
Publisher: Public Library of Science
Citation: PLoS ONE, 2009, 4 (10), pp. e7621-e7621
Abstract: Recent ecological studies in invertebrates show that the outcome of an infection is dependent on the specific pairing of host and parasite. Such specificity contrasts the long-held view that invertebrate innate immunity depends on a broad-spectrum recognition system. An important question is whether this specificity is due to the immune response rather than some other interplay between host and parasite genotypes. By measuring the expression of putative bumblebee homologues of antimicrobial peptides in response to infection by their gut trypanosome Crithidia bombi, we demonstrate that expression differences are associated with the specific interactions.
Recent ecological studies in invertebrates show that the outcome of an infection is dependent on the specific pairing of host and parasite. Such specificity contrasts the long-held view that invertebrate innate immunity depends on a broad-spectrum recognition system. An important question is whether this specificity is due to the immune response rather than some other interplay between host and parasite genotypes. By measuring the expression of putative bumblebee homologues of antimicrobial peptides in response to infection by their gut trypanosome Crithidia bombi, we demonstrate that expression differences are associated with the specific interactions.
DOI Link: 10.1371/journal.pone.0007621
ISSN: 1932-6203
eISSN: 1932-6203
Links: http://hdl.handle.net/2381/14291
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0007621
Type: Journal Article
Rights: Copyright: 2009 Riddell et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Description: Supplementary Material S1 Found at: doi:10.1371/journal.pone.0007621.s001 (0.05 MB DOC)
Appears in Collections:Published Articles, Dept. of Biology

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