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Title: Single-molecule enzymology: what can it tell us?
Other Titles: Single molecule enzymology: what can it tell us?
Authors: Bagshaw, Clive R.
First Published: Aug-2003
Publisher: The Biochemical Society
Citation: Biochemist, 2003, 25(4), pp.24-27
Abstract: In the last decade, several methods have been developed to measure enzyme activity at the level of a single enzyme molecule. This represents a considerable technical feat, but what does it allow us to learn about enzymes? Here, the basic principles are reviewed to show that new forms of heterogeneity in activity may be revealed and evidence gained for rare states that would otherwise be swamped in bulk assays.
Type: Article
Description: Also available via
Appears in Collections:Published Articles, Dept. of Biochemistry

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