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|Title:||Resuscitation-promoting factors reveal an occult population of tubercle Bacilli in Sputum.|
|Citation:||AM J RESPIR CRIT CARE MED, 2010, 181 (2), pp. 174-180|
|Abstract:||Resuscitation-promoting factors (Rpfs) are a family of secreted proteins produced by Mycobacterium tuberculosis (Mtb) that stimulate mycobacterial growth. Although mouse infection studies show that they support bacterial survival and disease reactivation, it is currently unknown whether Rpfs influence human infection. We hypothesized that tuberculous sputum might include a population of Rpf-dependent Mtb cells.|
|Appears in Collections:||Published Articles, Dept. of Infection, Immunity and Inflammation|
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