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Title: Molecular mechanisms of renal allograft fibrosis.
Authors: Waller, JR
Nicholson, ML
First Published: Nov-2001
Citation: BR J SURG, 2001, 88 (11), pp. 1429-1441
Abstract: Chronic graft nephropathy (CGN) remains the leading cause of renal allograft loss after the first year following transplantation. Histologically it is characterized by glomerulosclerosis, intimal hyperplasia and interstitial fibrosis. The pathogenesis is unclear, but is likely to involve both immunological and non-immunological factors. Despite improvements in short-term graft survival rates, new immunosuppressive regimens have made no impact on CGN.
DOI Link: 10.1046/j.0007-1323.2001.01867.x
ISSN: 0007-1323
Type: Journal Article
Appears in Collections:Published Articles, Dept. of Infection, Immunity and Inflammation

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