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Title: Microemulsion cyclosporin inhibits vascular remodelling and attenuates associated changes in profibrotic gene expression in an experimental model of allograft vasculopathy.
Authors: Murphy, GJ
Bicknell, GR
Nicholson, ML
First Published: Aug-2002
Citation: BR J SURG, 2002, 89 (8), pp. 1055-1061
Abstract: Chronic allograft dysfunction (CAD), the leading cause of solid organ transplant failure, is characterized by histological evidence of extracellular matrix (ECM) accumulation (fibrosis). The aim of this study was to characterize the changes in fibrosis-associated gene expression in an experimental model of CAD and to measure the effect of the immunosuppressant cyclosporin on these changes.
DOI Link: 10.1046/j.1365-2168.2002.02180.x
ISSN: 0007-1323
Type: Journal Article
Appears in Collections:Published Articles, Dept. of Infection, Immunity and Inflammation

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