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Title: Fibrosis-associated gene expression in renal transplant glomeruli after acute renal allograft rejection.
Authors: Brook, NR
White, SA
Waller, JR
Bicknell, GR
Nicholson, ML
First Published: Aug-2003
Citation: BR J SURG, 2003, 90 (8), pp. 1009-1014
Abstract: Acute allograft rejection is thought to be a risk factor for chronic allograft nephropathy, the cardinal features of which are vasculopathy, interstitial fibrosis and glomerulosclerosis. Fibrosis-associated genes might act as ad interim surrogate markers for chronic allograft nephropathy. The aim of this study was to determine mRNA expression of fibrosis-associated genes in glomeruli plucked from protocol renal transplant biopsies, in patients with or without a history of acute rejection.
DOI Link: 10.1002/bjs.4133
ISSN: 0007-1323
Type: Journal Article
Appears in Collections:Published Articles, Dept. of Infection, Immunity and Inflammation

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