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Title: Co-cultivation of mast cells and Fc epsilon RI alpha+ dendritic-like cells from human hip bone marrow.
Authors: Kaur, D
Berger, P
Duffy, SM
Brightling, CE
Bradding, P
First Published: Feb-2005
Citation: CLIN EXP ALLERGY, 2005, 35 (2), pp. 226-233
Abstract: Mast cells contribute to the pathogenesis of asthma and allergy through the release of a plethora of pro-inflammatory mediators and cytokines. Their study is hampered by the difficult access to human tissue samples. Human mast cells have been cultured from CD34+ progenitors in the bone marrow of normal volunteers following iliac crest bone marrow biopsy but this is invasive. Hip bone marrow could provide a more convenient less invasive source of mast cell progenitors.
DOI Link: 10.1111/j.1365-2222.2005.02161.x
ISSN: 0954-7894
Type: Journal Article
Appears in Collections:Published Articles, Dept. of Infection, Immunity and Inflammation

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