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|Title:||Potent activation of multiple signalling pathways by C-peptide in opossum kidney proximal tubular cells.|
|Citation:||DIABETOLOGIA, 2004, 47 (6), pp. 987-997|
|Abstract:||Proinsulin C-peptide is generally believed to be inert without any appreciable biological functions. However, it has been shown to modulate a variety of cellular processes important in the pathophysiology of diabetic complications. We therefore investigated the ability of C-peptide to stimulate intracellular signalling pathways in kidney proximal tubular cells, the altered activation of which may possibly be related to the development of diabetic nephropathy.|
|Appears in Collections:||Published Articles, Dept. of Infection, Immunity and Inflammation|
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