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|Title:||Pirfenidone inhibits early myointimal proliferation but has no effect on late lesion size in rats.|
|Citation:||EUR J VASC ENDOVASC SURG, 2002, 23 (3), pp. 234-240|
|Abstract:||intimal hyperplasia is mediated by smooth muscle cell proliferation, migration and deposition of extracellular matrix. The anti-fibrotic agent pirfenidone has been shown to inhibit pro-fibrotic growth factors in non-vascular inflammatory models. This study investigated the effect of the novel anti-fibrotic agent pirfenidone on the development of neointima.|
|Appears in Collections:||Published Articles, Dept. of Infection, Immunity and Inflammation|
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