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Title: Activation of human mast cells through the platelet-activating factor receptor.
Authors: Kajiwara, N
Sasaki, T
Bradding, P
Cruse, G
Sagara, H
Ohmori, K
Saito, H
Ra, C
Okayama, Y
First Published: May-2010
Citation: J ALLERGY CLIN IMMUNOL, 2010, 125 (5), pp. 1137-1.15E+09
Abstract: In human subjects platelet-activating factor (PAF) concentrations are markedly increased in the plasma after anaphylactic reactions, and these correlate strongly with the severity of the response. The mechanism for the systemic spread of mast cell (MC) activation in anaphylaxis is often assumed to relate to the hematogenous spread of allergen, but this is implausible, and amplification mechanisms need to be considered.
DOI Link: 10.1016/j.jaci.2010.01.056
eISSN: 1097-6825
Type: Journal Article
Appears in Collections:Published Articles, Dept. of Infection, Immunity and Inflammation

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