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Title: Carbon monoxide protects against ischemia-reperfusion injury in an experimental model of controlled nonheartbeating donor kidney.
Authors: Bagul, A
Hosgood, SA
Kaushik, M
Nicholson, ML
First Published: 27-Feb-2008
Citation: TRANSPLANTATION, 2008, 85 (4), pp. 576-581
Abstract: CO-releasing molecule-3 (CORM-3) is a transitional metal carbonyl that liberates carbon monoxide under appropriate conditions. Carbon monoxide exerts effects on intracellular apoptotic and inflammatory pathways, which suggest a role in reducing the effects of renal ischemia/reperfusion (I/R) injury. This study investigated the effects of CORM-3 administered at the time of reperfusion in a model of controlled nonheartbeating donor kidneys.
DOI Link: 10.1097/TP.0b013e318160516a
ISSN: 0041-1337
Type: Journal Article
Appears in Collections:Published Articles, Dept. of Infection, Immunity and Inflammation

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