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Title: Humoral and cellular immune responses up to 7.5 years after administration of streptokinase for acute myocardial infarction.
Authors: Squire, IB
Lawley, W
Fletcher, S
Holme, E
Hillis, WS
Hewitt, C
Woods, KL
First Published: Sep-1999
Citation: EUR HEART J, 1999, 20 (17), pp. 1245-1252
Abstract: Administration of streptokinase results in an immunological response which may lead to increased risk of anaphylactic reaction or reduced thrombolytic efficacy on repeat administration. For these reasons current recommendations suggest that streptokinase should not be given up to 1 year after first administration. We sought to define the profile of both the circulating antibody and T-cell response to streptokinase in patients who had received streptokinase up to 7.5 years previously following acute myocardial infarction.
DOI Link: 10.1053/euhj.1999.1528
ISSN: 0195-668X
Type: Journal Article
Appears in Collections:Published Articles, Dept. of Genetics

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