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|Title:||Psoriasis is associated with increased beta-defensin genomic copy number.|
van de Kerkhof PC
de Jongh G
den Heijer M
|Citation:||NAT GENET, 2008, 40 (1), pp. 23-25|
|Abstract:||Psoriasis is a common inflammatory skin disease with a strong genetic component. We analyzed the genomic copy number polymorphism of the beta-defensin region on human chromosome 8 in 179 Dutch individuals with psoriasis and 272 controls and in 319 German individuals with psoriasis and 305 controls. Comparisons in both cohorts showed a significant association between higher genomic copy number for beta-defensin genes and risk of psoriasis.|
|Appears in Collections:||Published Articles, Dept. of Genetics|
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