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|Title:||Expression of HIF-1alpha, HIF-2alpha (EPAS1), and their target genes in paraganglioma and pheochromocytoma with VHL and SDH mutations.|
|Citation:||J CLIN ENDOCRINOL METAB, 2006, 91 (11), pp. 4593-4598|
|Abstract:||Activation of the hypoxia-inducible transcription factors HIF-1 and HIF-2 and a HIF-independent defect in developmental apoptosis have been implicated in the pathogenesis of pheochromocytoma (PCC) associated with VHL, SDHB, and SDHD mutations.|
|Appears in Collections:||Published Articles, Dept. of Cancer Studies and Molecular Medicine|
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