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Title: Novel VEGF signalling inhibitors: how helpful are biomarkers in their early development?
Authors: Wood, J
Scott, E
Thomas, AL
First Published: Nov-2009
Citation: EXPERT OPIN INVESTIG DRUGS, 2009, 18 (11), pp. 1701-1714
Abstract: The development of vascular endothelial growth factor (VEGF) inhibitors of tumour angiogenesis can only be described as prolific. It is therefore interesting to speculate which will reach the clinic. Of course, the most effective agents will succeed, but how is effectiveness measured? When presented with a summary of competitive compounds, it can be difficult to discriminate between their potency on target, toxicity and response rates.
DOI Link: 10.1517/14728220903336466
eISSN: 1744-7658
Type: Journal Article
Appears in Collections:Published Articles, Dept. of Cancer Studies and Molecular Medicine

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