Please use this identifier to cite or link to this item:
Title: Urinary microalbumin/creatinine ratios: reference range in uncomplicated pregnancy.
Authors: Waugh, J
Bell, SC
Kilby, MD
Lambert, PC
Blackwell, CN
Shennan, A
Halligan, A
First Published: Feb-2003
Citation: CLIN SCI (LOND), 2003, 104 (2), pp. 103-107
Abstract: During uncomplicated pregnancy, the development of proteinuria is accepted as a poor prognostic sign and is associated with increasing maternal and perinatal mortality and morbidity. Physiological proteinuria increases with increasing gestation and one of its largest constituents is albumin. The reference range for the (micro)albumin/creatinine ratio (ACR) has not been described for normal pregnancy. This prospective cross-sectional study describes the gestation-specific 95% reference ranges for urinary microalbumin concentration, creatinine concentration and ACR in uncomplicated pregnancy. There is a significant increase ( P =0.016) in the ACR in the third trimester. The mean difference is 0.091 mg of albumin/mmol of creatinine (95% confidence interval, 0.014-0.168). Our results describe the first well-defined gestation-specific 95% reference range for a point-of-care measurement of the ACR. These data are essential if such testing is to be employed in antenatal care.
DOI Link: 10.1042/CS20020170
ISSN: 0143-5221
Type: Journal Article
Appears in Collections:Published Articles, Dept. of Cancer Studies and Molecular Medicine

Files in This Item:
There are no files associated with this item.

Items in LRA are protected by copyright, with all rights reserved, unless otherwise indicated.