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Title: WNT5A expression increases during melanoma progression and correlates with outcome.
Authors: Da Forno PD
Pringle, JH
Hutchinson, P
Osborn, J
Huang, Q
Potter, L
Hancox, RA
Fletcher, A
Saldanha, GS
First Published: 15-Sep-2008
Citation: CLIN CANCER RES, 2008, 14 (18), pp. 5825-5832
Abstract: Wnt ligands play a major role in development and are important in cancer. Expression microarray analysis correlates one member of this family, WNT5A, to a subclass of melanomas with increased motility and invasion. There are no large studies of clinical samples primarily addressing the importance of WNT5A in melanoma progression or outcome. Therefore, this study aimed to assess the protein expression of WNT5A during melanoma progression and its effect on outcome.
DOI Link: 10.1158/1078-0432.CCR-07-5104
ISSN: 1078-0432
Type: Journal Article
Appears in Collections:Published Articles, Dept. of Cancer Studies and Molecular Medicine

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