Please use this identifier to cite or link to this item: http://hdl.handle.net/2381/16397
Title: Nociceptin and urotensin-II concentrations in critically ill patients with sepsis.
Authors: Williams, JP
Thompson, JP
Young, SP
Gold, SJ
McDonald, J
Rowbotham, DJ
Lambert, DG
First Published: Jun-2008
Citation: BR J ANAESTH, 2008, 100 (6), pp. 810-814
Abstract: The systemic inflammatory response to infection (sepsis) involves widespread organ dysfunction, including changes in immune modulation, cardiovascular derangements, and neural activation. Two neuropeptide/receptor systems, nociceptin/orphanin FQ (N/OFQ) which acts at the non-classical opioid receptor NOP and urotensin-II (U-II) which acts at the urotensin receptor (UT), have been implicated in neural, immune, and cardiovascular system function. In this study, we make measurements of these peptides in critically ill patients.
DOI Link: 10.1093/bja/aen093
eISSN: 1471-6771
Links: http://hdl.handle.net/2381/16397
Type: Journal Article
Appears in Collections:Published Articles, Dept. of Health Sciences

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