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|Title:||Nociceptin and urotensin-II concentrations in critically ill patients with sepsis.|
|Citation:||BR J ANAESTH, 2008, 100 (6), pp. 810-814|
|Abstract:||The systemic inflammatory response to infection (sepsis) involves widespread organ dysfunction, including changes in immune modulation, cardiovascular derangements, and neural activation. Two neuropeptide/receptor systems, nociceptin/orphanin FQ (N/OFQ) which acts at the non-classical opioid receptor NOP and urotensin-II (U-II) which acts at the urotensin receptor (UT), have been implicated in neural, immune, and cardiovascular system function. In this study, we make measurements of these peptides in critically ill patients.|
|Appears in Collections:||Published Articles, Dept. of Health Sciences|
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