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|Title:||The interleukin-10-1082 'A' allele and abdominal aortic aneurysms.|
|Citation:||J VASC SURG, 2007, 46 (4), pp. 687-693|
|Abstract:||Abdominal aortic aneurysms (AAA) are caused by inflammatory processes in the wall of the aorta resulting in degradation of structural proteins. This inflammatory process is mediated, in part, by cytokines, and interleukin-10 (IL-10) is a predominantly anti-inflammatory cytokine. A single nucleotide polymorphism in the promoter region of the IL-10 gene that affects transcription has been associated with AAA in a small study. The aim of this study was to determine whether this polymorphism is associated with AAA and also examine its effect on the growth of small AAA.|
|Appears in Collections:||Published Articles, Dept. of Cardiovascular Sciences|
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