Please use this identifier to cite or link to this item: http://hdl.handle.net/2381/16762
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dc.contributor.authorBown, MJ-
dc.contributor.authorLloyd, GM-
dc.contributor.authorSandford, RM-
dc.contributor.authorThompson, JR-
dc.contributor.authorLondon, NJ-
dc.contributor.authorSamani, NJ-
dc.contributor.authorSayers, RD-
dc.date.accessioned2012-10-24T09:02:16Z-
dc.date.available2012-10-24T09:02:16Z-
dc.date.issued2007-10-
dc.identifier.citationJ VASC SURG, 2007, 46 (4), pp. 687-693-
dc.identifier.issn0741-5214-
dc.identifier.urihttp://hdl.handle.net/2381/16762-
dc.description.abstractAbdominal aortic aneurysms (AAA) are caused by inflammatory processes in the wall of the aorta resulting in degradation of structural proteins. This inflammatory process is mediated, in part, by cytokines, and interleukin-10 (IL-10) is a predominantly anti-inflammatory cytokine. A single nucleotide polymorphism in the promoter region of the IL-10 gene that affects transcription has been associated with AAA in a small study. The aim of this study was to determine whether this polymorphism is associated with AAA and also examine its effect on the growth of small AAA.-
dc.formatmetadata-
dc.language.isoeng-
dc.sourcePubMed-
dc.source.urihttp://www.ncbi.nlm.nih.gov/pubmed/-
dc.subjectAged-
dc.subjectAged-
dc.subject80 and over-
dc.subjectAlleles-
dc.subjectAortic Aneurysm-
dc.subjectAbdominal-
dc.subjectCase-Control Studies-
dc.subjectFemale-
dc.subjectGene Frequency-
dc.subjectGenotype-
dc.subjectHumans-
dc.subjectInterleukin-10-
dc.subjectMale-
dc.subjectMiddle Aged-
dc.subjectPolymorphism-
dc.subjectSingle Nucleotide-
dc.subjectPromoter Regions-
dc.subjectGenetic-
dc.titleThe interleukin-10-1082 'A' allele and abdominal aortic aneurysms.-
dc.typeJournal Article-
dc.identifier.doi10.1016/j.jvs.2007.06.025-
dc.identifier.piiS0741-5214(07)00996-2-
dc.description.irispid19620-
Appears in Collections:Published Articles, Dept. of Cardiovascular Sciences

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