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Title: Aortic aneurysms secrete interleukin-6 into the circulation.
Authors: Dawson, J
Cockerill, GW
Choke, E
Belli, AM
Loftus, I
Thompson, MM
First Published: Feb-2007
Citation: J VASC SURG, 2007, 45 (2), pp. 350-356
Abstract: Circulating plasma interleukin-6 (IL-6) concentrations are elevated in patients with abdominal aortic aneurysms (AAAs) compared with controls. In vitro studies suggest that the aneurysm is the source of the IL-6. Because IL-6 is an independent risk factor for cardiovascular mortality, elevation of this cytokine may be significant in these patients, who represent a group at increased risk from cardiovascular death. The aim of this study was to directly measure in vivo aortic IL-6 concentrations, testing the hypothesis that aneurysms secrete IL-6 into the circulation.
DOI Link: 10.1016/j.jvs.2006.09.049
ISSN: 0741-5214
Type: Journal Article
Appears in Collections:Published Articles, Dept. of Cardiovascular Sciences

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