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Title: Design of the Coronary ARtery DIsease Genome-Wide Replication And Meta-Analysis (CARDIoGRAM) Study: A Genome-wide association meta-analysis involving more than 22 000 cases and 60 000 controls.
Authors: Preuss, M
König, IR
Thompson, JR
Erdmann, J
Absher, D
Assimes, TL
Blankenberg, S
Boerwinkle, E
Chen, L
Cupples, LA
Hall, AS
Halperin, E
Hengstenberg, C
Holm, H
Laaksonen, R
Li, M
März, W
McPherson, R
Musunuru, K
Nelson, CP
Burnett, MS
Epstein, SE
O'Donnell, CJ
Quertermous, T
Rader, DJ
Roberts, R
Schillert, A
Stefansson, K
Stewart, AF
Thorleifsson, G
Voight, BF
Wells, GA
Ziegler, A
Kathiresan, S
Reilly, MP
Samani, NJ
Schunkert, H
CARDIoGRAM, Consortium
First Published: Oct-2010
Citation: CIRC CARDIOVASC GENET, 2010, 3 (5), pp. 475-483
Abstract: Recent genome-wide association studies (GWAS) of myocardial infarction (MI) and other forms of coronary artery disease (CAD) have led to the discovery of at least 13 genetic loci. In addition to the effect size, power to detect associations is largely driven by sample size. Therefore, to maximize the chance of finding novel susceptibility loci for CAD and MI, the Coronary ARtery DIsease Genome-wide Replication And Meta-analysis (CARDIoGRAM) consortium was formed.
DOI Link: 10.1161/CIRCGENETICS.109.899443
eISSN: 1942-3268
Type: Journal Article
Appears in Collections:Published Articles, Dept. of Cardiovascular Sciences

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