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Title: Gene expression profile of abdominal aortic aneurysm rupture.
Authors: Choke, E
Thompson, MM
Jones, A
Torsney, E
Dawson, J
Laing, K
Nasr, H
Loftus, IM
Cockerill, GW
First Published: Nov-2006
Citation: ANN N Y ACAD SCI, 2006, 1085, pp. 311-314
Abstract: To search for novel transcriptional pathways that are activated in abdominal aortic aneurysm rupture, cDNA microarrays were used to compare global mRNA expression at the aneurysm rupture edge to anterior sac, and selected results were confirmed using quantitative real-time-polymerase chain reaction (QRT-PCR). This study identified apoptosis, angiogenesis, and inflammation as potentially important participants during the process of aneurysm rupture.
DOI Link: 10.1196/annals.1383.006
ISSN: 0077-8923
Type: Journal Article
Appears in Collections:Published Articles, Dept. of Cardiovascular Sciences

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