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Title: The role of the CCR5 Delta32 polymorphism in abdominal aortic aneurysms.
Authors: Sandford, B
Bown, M
London, N
Sayers, R
First Published: Aug-2009
Citation: INT J IMMUNOGENET, 2009, 36 (4), pp. 199-205
Abstract: C-C chemokine receptor 5 (CCR5) is involved in the regulation of the inflammatory response. Abdominal aortic aneurysms (AAA) may arise as the result of a chronic inflammatory process which is influenced by genetic predisposition. The CCR5 gene is associated with a 32 base pair deletion (the Delta32 polymorphism). The aim of this study was to investigate the role of the CCR5 Delta32 polymorphism in the development of AAA.
DOI Link: 10.1111/j.1744-313X.2009.00845.x
eISSN: 1744-313X
Type: Journal Article
Appears in Collections:Published Articles, Dept. of Cardiovascular Sciences

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