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Title: Toll-like receptor 4 signalling is neither sufficient nor required for oxidised phospholipid mediated induction of interleukin-8 expression.
Authors: Erridge, C
Webb, DJ
Spickett, CM
First Published: Jul-2007
Citation: ATHEROSCLEROSIS, 2007, 193 (1), pp. 77-85
Abstract: Toll-like receptor (TLR)-4 signalling has been shown to accelerate atherosclerosis. As oxidised phospholipids are present in atherosclerotic plaque and have been shown to modulate TLR4 signalling, we investigated the role of oxidised 1-palmitoyl-2-arachidonyl-sn-glycero-3-phosphorylcholine (OxPAPC) in the regulation of TLR 1, 2, 4 and 6 signalling.
DOI Link: 10.1016/j.atherosclerosis.2006.08.032
ISSN: 0021-9150
Type: Journal Article
Appears in Collections:Published Articles, Dept. of Cardiovascular Sciences

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