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Title: Toll-like receptor-dependent lipid body formation in macrophage foam cell formation.
Authors: Nicolaou, G
Erridge, C
First Published: Oct-2010
Citation: CURR OPIN LIPIDOL, 2010, 21 (5), pp. 427-433
Abstract: The differentiation of macrophages into lipid-laden foam cells is central to the development of atherosclerosis. Traditionally, it has been assumed that the uptake of oxidized low-density lipoprotein by macrophage scavenger receptors is largely responsible for this process. However, in light of recent evidence that these mechanisms may not play as large a role as previously thought, alternative mechanisms of foam cell formation are now being explored.
DOI Link: 10.1097/MOL.0b013e32833cacd5
eISSN: 1473-6535
Type: Journal Article
Appears in Collections:Published Articles, Dept. of Cardiovascular Sciences

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