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Title: Under arrest in mitosis: Cdc20 dies twice.
Authors: Fry, AM
Yamano, H
First Published: Dec-2008
Citation: NAT CELL BIOL, 2008, 10 (12), pp. 1385-1387
Abstract: The spindle assembly checkpoint is crucial for maintaining genome integrity in dividing cells by preventing premature chromosome segregation. Degradation of the APC/C activator Cdc20 seems to be an essential and conserved mechanism to maintain this checkpoint in the presence of chromosomes that are not attached to the mitotic spindle.
DOI Link: 10.1038/ncb1208-1385
eISSN: 1476-4679
Type: Journal Article
Appears in Collections:Published Articles, Dept. of Biochemistry

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