Please use this identifier to cite or link to this item:
Title: Dense genotyping of candidate gene loci identifies variants associated with high-density lipoprotein cholesterol.
Authors: Edmondson, AC
Braund, PS
Stylianou, IM
Khera, AV
Nelson, CP
Wolfe, ML
Derohannessian, SL
Keating, BJ
Qu, L
He, J
Tobin, MD
Tomaszewski, M
Baumert, J
Klopp, N
Döring, A
Thorand, B
Li, M
Reilly, MP
Koenig, W
Samani, NJ
Rader, DJ
First Published: Apr-2011
Citation: CIRC CARDIOVASC GENET, 2011, 4 (2), pp. 145-155
Abstract: Plasma levels of high-density lipoprotein cholesterol (HDL-C) are known to be heritable, but only a fraction of the heritability is explained. We used a high-density genotyping array containing single-nucleotide polymorphisms (SNPs) from HDL-C candidate genes selected on known biology of HDL-C metabolism, mouse genetic studies, and human genetic association studies. SNP selection was based on tagging SNPs and included low-frequency nonsynonymous SNPs.
DOI Link: 10.1161/CIRCGENETICS.110.957563
eISSN: 1942-3268
Type: Journal Article
Appears in Collections:Published Articles, Dept. of Cardiovascular Sciences

Files in This Item:
There are no files associated with this item.

Items in LRA are protected by copyright, with all rights reserved, unless otherwise indicated.