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Title: A spatial model of cellular molecular trafficking including active transport along microtubules.
Authors: Cangiani, A
Natalini, R
First Published: 21-Dec-2010
Citation: J THEOR BIOL, 2010, 267 (4), pp. 614-625
Abstract: We consider models of Ran-driven nuclear transport of molecules such as proteins in living cells. The mathematical model presented is the first to take into account for the active transport of molecules along the cytoplasmic microtubules. All parameters entering the models are thoroughly discussed. The model is tested by numerical simulations based on discontinuous Galerkin finite element methods. The numerical experiments are compared to the behavior observed experimentally.
DOI Link: 10.1016/j.jtbi.2010.08.017
eISSN: 1095-8541
Type: Journal Article
Appears in Collections:Published Articles, Dept. of Mathematics

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