Please use this identifier to cite or link to this item: http://hdl.handle.net/2381/18150
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dc.contributor.authorCangiani, A-
dc.contributor.authorNatalini, R-
dc.date.accessioned2012-10-24T09:04:50Z-
dc.date.available2012-10-24T09:04:50Z-
dc.date.issued2010-12-21-
dc.identifier.citationJ THEOR BIOL, 2010, 267 (4), pp. 614-625-
dc.identifier.urihttp://hdl.handle.net/2381/18150-
dc.description.abstractWe consider models of Ran-driven nuclear transport of molecules such as proteins in living cells. The mathematical model presented is the first to take into account for the active transport of molecules along the cytoplasmic microtubules. All parameters entering the models are thoroughly discussed. The model is tested by numerical simulations based on discontinuous Galerkin finite element methods. The numerical experiments are compared to the behavior observed experimentally.-
dc.formatmetadata-
dc.language.isoeng-
dc.sourcePubMed-
dc.source.urihttp://www.ncbi.nlm.nih.gov/pubmed/-
dc.subjectBiological Transport-
dc.subjectActive-
dc.subjectCells-
dc.subjectDiffusion-
dc.subjectKaryopherins-
dc.subjectKinetics-
dc.subjectMicrotubules-
dc.subjectModels-
dc.subjectBiological-
dc.subjectNuclear Envelope-
dc.subjectNumerical Analysis-
dc.subjectComputer-Assisted-
dc.subjectPermeability-
dc.subjectRetinoblastoma Protein-
dc.titleA spatial model of cellular molecular trafficking including active transport along microtubules.-
dc.typeJournal Article-
dc.identifier.doi10.1016/j.jtbi.2010.08.017-
dc.identifier.eissn1095-8541-
dc.identifier.piiS0022-5193(10)00426-1-
dc.description.irispid41497-
Appears in Collections:Published Articles, Dept. of Mathematics

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