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Title: Production and inhibition of the gelatinolytic matrix metalloproteinases in a human model of vein graft stenosis.
Authors: Porter, KE
Thompson, MM
Loftus, IM
McDermott, E
Jones, L
Crowther, M
Bell, PR
London, NJ
First Published: May-1999
Citation: EUR J VASC ENDOVASC SURG, 1999, 17 (5), pp. 404-412
Abstract: human vein graft stenoses are caused by intimal hyperplasia, a process which is characterised by extensive degradation and accumulation of extracellular matrix. This study investigated the role of the matrix metalloproteinases (MMPs) - the principal physiological mediators of extracellular matrix degradation - in the development of intimal hyperplasia in cultured human long saphenous vein.
DOI Link: 10.1053/ejvs.1998.0761
ISSN: 1078-5884
Type: Journal Article
Appears in Collections:Published Articles, Dept. of Cardiovascular Sciences

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