Please use this identifier to cite or link to this item:
Title: G-protein-coupled receptor phosphorylation and palmitoylation.
Authors: Tobin, AB
Wheatley, M
First Published: 2004
Citation: METHODS MOL BIOL, 2004, 259, pp. 275-281
Abstract: It is now clear that nearly all G-protein-coupled receptors (GPCRs) are phosphorylated and palmitolyated. The process of receptor phosphorylation has been extensively studied because it offers a regulatory mechanism that is both rapid and dynamic. However, it has recently become clear that palmitoyaltion of GPCRs at C-terminal cysteine residues may also offer dynamic receptor modification. A growing number of GPCRs have been demonstrated to undergo rapid agonist-mediated changes in their palmitoylation status with functional implications to receptor signaling. This chapter aims to outline the methods we have used to investigate agonist-mediated changes in GPCR phosphorylation and palmitoylation.
DOI Link: 10.1385/1-59259-754-8:275
ISSN: 1064-3745
Type: Journal Article
Appears in Collections:Published Articles, Dept. of Cell Physiology and Pharmacology

Files in This Item:
There are no files associated with this item.

Items in LRA are protected by copyright, with all rights reserved, unless otherwise indicated.