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Title: Intragraft expression of transforming growth factor beta1 gene in isolated glomeruli from human renal transplants.
Authors: Nicholson, ML
Bicknell, GR
Barker, G
Doughman, TM
Williams, ST
Furness, PN
First Published: Sep-1999
Citation: BR J SURG, 1999, 86 (9), pp. 1144-1148
Abstract: Experimental evidence suggests that transforming growth factor (TGF) beta1 is a fibrogenic cytokine. The histopathological changes of chronic renal allograft nephropathy are dominated by fibrotic changes and TGF-beta may have an important aetiological role. This study investigated the relationship between intragraft TGF-beta gene expression and extracellular matrix protein deposition in human renal allografts.
DOI Link: 10.1046/j.1365-2168.1999.01202.x
ISSN: 0007-1323
Type: Journal Article
Appears in Collections:Published Articles, Dept. of Infection, Immunity and Inflammation

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