Please use this identifier to cite or link to this item: http://hdl.handle.net/2381/22893
Title: Red cell Na+/Li+ countertransport and Na+/H+ exchanger isoforms in human proximal tubules.
Authors: Ng, LL
Quinn, PA
Baker, F
Carr, SJ
First Published: Jul-2000
Citation: KIDNEY INT, 2000, 58 (1), pp. 229-235
Abstract: Increased activity of the Na+/Li+ countertransporter (SLC) is a well-recognized intermediate phenotype of hypertension and diabetic nephropathy and may indicate a predisposition to hypertension. Previous work has attempted to link this membrane transport marker to altered Na+ reabsorption in the proximal tubule. Since the Na+/H+ exchanger (NHE) isoforms 1 and 3 are expressed in the basolateral and apical membranes of the proximal tubule, respectively, we investigated the relationship between these transport proteins and red cell SLC to examine whether the peripheral blood transport phenotype is associated with altered levels of transport proteins in the proximal tubule.
DOI Link: 10.1046/j.1523-1755.2000.00157.x
ISSN: 0085-2538
Links: http://hdl.handle.net/2381/22893
Type: Journal Article
Appears in Collections:Published Articles, Dept. of Cardiovascular Sciences

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