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Title: Differential effects of cyclosporin and tacrolimus on the expression of fibrosis-associated genes in isolated glomeruli from renal transplants.
Authors: Bicknell, GR
Williams, ST
Shaw, JA
Pringle, JH
Furness, PN
Nicholson, ML
First Published: Nov-2000
Citation: BR J SURG, 2000, 87 (11), pp. 1569-1575
Abstract: Chronic allograft nephropathy is characterized by an excessive accumulation of extracellular matrix proteins leading to glomerular and interstitial fibrosis. The aim of this study was to determine the effects of two different immunosuppressive agents (cyclosporin and tacrolimus) on the expression of the genes controlling extracellular matrix deposition in renal transplant glomeruli.
DOI Link: 10.1046/j.1365-2168.2000.01577.x
ISSN: 0007-1323
Type: Journal Article
Appears in Collections:Published Articles, Dept. of Cancer Studies and Molecular Medicine

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