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Title: Growth differentiation factor-15 as a prognostic marker in patients with acute myocardial infarction.
Authors: Khan, SQ
Ng, K
Dhillon, O
Kelly, D
Quinn, P
Squire, IB
Davies, JE
Ng, LL
First Published: May-2009
Citation: EUR HEART J, 2009, 30 (9), pp. 1057-1065
Abstract: Our aim was to assess the long-term prognostic value of growth differentiation factor-15 (GDF-15) in patients post-acute myocardial infarction (AMI). Growth differentiation factor-15 is a member of the transforming growth factor beta family. Growth differentiation factor-15 is expressed in the myocardium and upregulated due to 'stress' and has been shown to have antiapoptotic actions. Its role in the cardiovascular system however is not well defined. We were interested to see if GDF-15 could provide long-term prognostic value in post-AMI patients. We compared GDF-15 with N-terminal pro-B-type natriuretic peptide (NT-proBNP).
DOI Link: 10.1093/eurheartj/ehn600
eISSN: 1522-9645
Type: Journal Article
Appears in Collections:Published Articles, Dept. of Cardiovascular Sciences

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