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Title: Levonorgestrel intrauterine system for endometrial protection in women with breast cancer on adjuvant tamoxifen.
Authors: Chin, J
Konje, JC
Hickey, M
First Published: 2009
Citation: COCHRANE DATABASE SYST REV, 2009 (4), pp. CD007245-CD007245
Abstract: Adjuvant tamoxifen reduces the risk of breast cancer recurrence in women with estrogen receptor-positive breast cancer. Tamoxifen also increases the risk of postmenopausal bleeding, endometrial hyperplasia, polyps, and endometrial cancer. The levonorgestrel-releasing intrauterine system (LNG-IUS) causes profound endometrial suppression. This systematic review considered the evidence that the LNG-IUS prevents the development of endometrial pathology in women taking tamoxifen as adjuvant endocrine therapy for breast cancer.
DOI Link: 10.1002/14651858.CD007245.pub2
eISSN: 1469-493X
Type: Journal Article
Appears in Collections:Published Articles, Dept. of Cancer Studies and Molecular Medicine

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