Please use this identifier to cite or link to this item: http://hdl.handle.net/2381/23568
Title: The role of sex steroid hormones, cytokines and the endocannabinoid system in female fertility.
Authors: Karasu, T
Marczylo, TH
Maccarrone, M
Konje, JC
First Published: May-2011
Citation: HUM REPROD UPDATE, 2011, 17 (3), pp. 347-361
Abstract: Marijuana, the most used recreational drug, has been shown to have adverse effects on human reproduction. Endogenous cannabinoids (also called endocannabinoids) bind to the same receptors as those of Δ(9)-tetrahydrocannabinol (THC), the psychoactive component of Cannabis sativa. The most extensively studied endocannabinoids are anandamide (N-arachidonoylethanolamine, AEA) and 2-arachidonoylglycerol. The endocannabinoids, their congeners and the cannabinoid receptors, together with the metabolic enzymes and putative transporters form the endocannabinoid system (ECS). In this review, we summarize current knowledge about the relationships of ECS, sex steroid hormones and cytokines in female fertility, and underline the importance of this endocannabinoid-hormone-cytokine network.
DOI Link: 10.1093/humupd/dmq058
eISSN: 1460-2369
Links: http://hdl.handle.net/2381/23568
Type: Journal Article
Appears in Collections:Published Articles, Dept. of Cancer Studies and Molecular Medicine

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