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Title: Molecular aspects of melanoma.
Authors: Da Forno PD
Saldanha, GS
First Published: Jun-2011
Citation: CLIN LAB MED, 2011, 31 (2), pp. 331-343
Abstract: Melanoma is the most serious type of skin cancer. Unfortunately, treatment has progressed little and advanced melanoma has appalling survival rates. A goal of molecular analysis is to fully describe the alterations that underpin melanoma's clinical phenotype so that diagnosis can be more accurate, outcome can be predicted with greater confidence, and treatment that is tailored to the patient can be given. This article describes the handful of "signature" changes that are known to occur, describes how some recent studies have shed light on changes beyond this signature, and finally discusses the impact of molecular pathology for practicing histopathologists.
DOI Link: 10.1016/j.cll.2011.03.010
eISSN: 1557-9832
Type: Journal Article
Appears in Collections:Published Articles, Dept. of Cancer Studies and Molecular Medicine

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