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Title: Rate of decline in renal function in Indo-Asians and Whites with diabetic nephropathy.
Authors: Koppiker, N
Feehally, J
Raymond, N
Abrams, KR
Burden, AC
First Published: Jan-1998
Citation: DIABET MED, 1998, 15 (1), pp. 60-65
Abstract: The incidence of end-stage renal failure (ESRF) is higher in the Indo-Asian ethnic group as compared to the White. To investigate whether this might be associated with faster rates of progression to ESRF in Indo-Asian diabetic patients, we studied a total of 39 Type 2 diabetic patients, using the Department of Nephrology database showing serial serum creatinine measurements from the time of first referral to the clinic until they reached a level of >500 micromol l(-1) or ESRF requiring renal replacement therapy (RRT), either dialysis or renal transplantation. They were grouped into Indo-Asian (n = 24) and White (n = 15). The rate of progression of those who developed ESRF, calculated as the slope of log serum creatinine against time, was not significantly different between the Indo-Asian and White patients, p = 0.73. We conclude that the higher incidence of ESRF in the Indo-Asian Type 2 diabetic patient with nephropathy is therefore not due to a faster rate of deterioration in renal function.
DOI Link: 10.1002/(SICI)1096-9136(199801)15:1<60::AID-DIA525>3.0.CO;2-R
ISSN: 0742-3071
Type: Journal Article
Appears in Collections:Published Articles, Dept. of Infection, Immunity and Inflammation

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